Assay interference and recovery controls

// Distinguish matrix interference, recovery and dilution linearity in assay development.
// Synthetic worked example: all entities, schedules and measurements are illustrative.
// Every string below is EXAMPLE text from a fictional model: replace it.
// Replace assumptions and inputs before applying this model to actual work.

experiment design {
  title: "Illustrative Assay interference and recovery controls"
  model: "Independent sample aliquots"
}

// Six independent units per condition; technical repeats do not increase n.
sample per_condition {
  n: 6
  replicates: 1
}

condition condition_0 {
  title: "Matrix blank"
  dose: "Blank matrix"
  duration: "Single analytical batch"
}

condition condition_1 {
  title: "Unspiked sample"
  dose: "Unspiked sample"
  duration: "Single analytical batch"
}

condition condition_2 {
  title: "Low spike"
  dose: "Low reference spike"
  duration: "Single analytical batch"
}

condition condition_3 {
  title: "High spike"
  dose: "High reference spike"
  duration: "Single analytical batch"
}

assay assay_0 {
  kind: "Measured signal"
  readout: "Prespecified measurement; no observed results supplied"
}

assay assay_1 {
  kind: "Spike recovery"
  readout: "Prespecified measurement; no observed results supplied"
}

assay assay_2 {
  kind: "Dilution response"
  readout: "Prespecified measurement; no observed results supplied"
}

view design_flow: experiment_flow(design)