TRIPOD — Prediction Model
Development + validation pipeline for a clinical prediction model.
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flowchart LR
Cohort[Source cohort\nN = 12,420] --> Excl[Apply eligibility]
Excl --> Anal[Analytical cohort\nN = 8,944]
Anal --> Dev[Development set 70%\nn = 6,261]
Anal --> Val[Validation set 30%\nn = 2,683]
Dev --> Sel[Variable selection +\nmodel building]
Sel --> Cal[Internal calibration]
Cal --> Lock[Lock model]
Lock --> Apply[Apply to validation set]
Val --> Apply
Apply --> Metric[AUC, calibration slope,\nBrier score, decision curve]