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Causal DAG templates

Biology — Mendelian Randomization

A genetic variant as an instrumental variable.

Causal DAGLife SciencesCausal DAG syntax docs
Template previewCausal DAG
Mendelian randomizationGGenetic variant (IV)XExposureYOutcomeUConfoundersExposureOutcomeConfounderMediatorUnobservedNo adjustment set works — but `Genetic variant (IV)` is an instrument, which identifies the effect under the usual instrumental-variable assum…No adjustment set works here — and `Genetic variant (IV)` is an INSTRUMENT: it moves the exposure, and this diagram gives it no path to the outcome except through…

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title "Mendelian randomization"
node G "Genetic variant (IV)"
exposure X "Exposure"
outcome Y "Outcome"
unobserved U "Confounders"
G -> X
X -> Y
U -> X
U -> Y