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Biology — G-Protein Cycle

Activation and inactivation of a heterotrimeric G-protein.

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{
  "elements":[
    {"data":{"id":"ligand","label":"Ligand binds GPCR"}},
    {"data":{"id":"gdp","label":"G-protein (GDP)"}},
    {"data":{"id":"exchange","label":"GDP -> GTP exchange"}},
    {"data":{"id":"alpha","label":"Galpha-GTP dissociates"}},
    {"data":{"id":"effector","label":"Activates effector"}},
    {"data":{"id":"gtpase","label":"GTP hydrolysed"}},
    {"data":{"id":"reassoc","label":"Reassociates (off)"}},
    {"data":{"source":"ligand","target":"gdp"}},
    {"data":{"source":"gdp","target":"exchange"}},
    {"data":{"source":"exchange","target":"alpha"}},
    {"data":{"source":"alpha","target":"effector"}},
    {"data":{"source":"alpha","target":"gtpase"}},
    {"data":{"source":"gtpase","target":"reassoc"}}
  ],
  "layout":{"name":"breadthfirst","directed":true}
}