Biology — G-Protein Cycle
Activation and inactivation of a heterotrimeric G-protein.
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{
"elements":[
{"data":{"id":"ligand","label":"Ligand binds GPCR"}},
{"data":{"id":"gdp","label":"G-protein (GDP)"}},
{"data":{"id":"exchange","label":"GDP -> GTP exchange"}},
{"data":{"id":"alpha","label":"Galpha-GTP dissociates"}},
{"data":{"id":"effector","label":"Activates effector"}},
{"data":{"id":"gtpase","label":"GTP hydrolysed"}},
{"data":{"id":"reassoc","label":"Reassociates (off)"}},
{"data":{"source":"ligand","target":"gdp"}},
{"data":{"source":"gdp","target":"exchange"}},
{"data":{"source":"exchange","target":"alpha"}},
{"data":{"source":"alpha","target":"effector"}},
{"data":{"source":"alpha","target":"gtpase"}},
{"data":{"source":"gtpase","target":"reassoc"}}
],
"layout":{"name":"breadthfirst","directed":true}
}