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Biology — Insulin Secretion

How a beta cell senses glucose and releases insulin.

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{
  "elements":[
    {"data":{"id":"glucose","label":"High blood glucose"}},
    {"data":{"id":"uptake","label":"GLUT2 uptake"}},
    {"data":{"id":"atp","label":"ATP rises"}},
    {"data":{"id":"katp","label":"K-ATP channels close"}},
    {"data":{"id":"depol","label":"Depolarisation"}},
    {"data":{"id":"ca","label":"Ca2+ influx"}},
    {"data":{"id":"insulin","label":"Insulin released"}},
    {"data":{"source":"glucose","target":"uptake"}},
    {"data":{"source":"uptake","target":"atp"}},
    {"data":{"source":"atp","target":"katp"}},
    {"data":{"source":"katp","target":"depol"}},
    {"data":{"source":"depol","target":"ca"}},
    {"data":{"source":"ca","target":"insulin"}}
  ],
  "layout":{"name":"breadthfirst","directed":true}
}