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Biology — MHC Class I Presentation

Displaying intracellular peptides to CD8+ T cells.

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{
  "elements":[
    {"data":{"id":"pathogen","label":"Intracellular protein"}},
    {"data":{"id":"proteasome","label":"Proteasome digests"}},
    {"data":{"id":"peptide","label":"Peptide fragments"}},
    {"data":{"id":"mhc1","label":"Loaded onto MHC class I"}},
    {"data":{"id":"surface","label":"Displayed on cell surface"}},
    {"data":{"id":"cd8","label":"CD8+ T cell recognises"}},
    {"data":{"id":"kill","label":"Infected cell killed"}},
    {"data":{"source":"pathogen","target":"proteasome"}},
    {"data":{"source":"proteasome","target":"peptide"}},
    {"data":{"source":"peptide","target":"mhc1"}},
    {"data":{"source":"mhc1","target":"surface"}},
    {"data":{"source":"surface","target":"cd8"}},
    {"data":{"source":"cd8","target":"kill"}}
  ],
  "layout":{"name":"breadthfirst","directed":true}
}