Biology — MHC Class I Presentation
Displaying intracellular peptides to CD8+ T cells.
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{
"elements":[
{"data":{"id":"pathogen","label":"Intracellular protein"}},
{"data":{"id":"proteasome","label":"Proteasome digests"}},
{"data":{"id":"peptide","label":"Peptide fragments"}},
{"data":{"id":"mhc1","label":"Loaded onto MHC class I"}},
{"data":{"id":"surface","label":"Displayed on cell surface"}},
{"data":{"id":"cd8","label":"CD8+ T cell recognises"}},
{"data":{"id":"kill","label":"Infected cell killed"}},
{"data":{"source":"pathogen","target":"proteasome"}},
{"data":{"source":"proteasome","target":"peptide"}},
{"data":{"source":"peptide","target":"mhc1"}},
{"data":{"source":"mhc1","target":"surface"}},
{"data":{"source":"surface","target":"cd8"}},
{"data":{"source":"cd8","target":"kill"}}
],
"layout":{"name":"breadthfirst","directed":true}
}