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Genetics pedigree templates

Biology — Pedigree: Fabry disease (X-linked)

X-linked lysosomal storage disorder.

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Fabry disease (X-linked)I1I2II1II2Unaffected maleUnaffected femaleAffectedCarrierConsistent with 4 modes — autosomal dominant, autosomal recessive, X-linked recessive, m…Consistent with 4 modes: autosomal dominant, autosomal recessive, X-linked recessive, mitochondrial. …X-linked dominant is ruled out: II1 is an unaffected daughter of the affected I1. He has one X and gi…Y-linked is ruled out: II2 is an unaffected son of the affected I1. A Y-linked trait passes to every …

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title "Fabry disease (X-linked)"
individual I1 sex male affected yes gen 1
individual I2 sex female affected no gen 1
mating I1 I2
individual II1 sex female affected no carrier yes gen 2 parents I1 I2
individual II2 sex male affected no gen 2 parents I1 I2