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Genetics pedigree templates

Biology — Pedigree: myotonic dystrophy (AD)

Autosomal dominant trinucleotide-repeat disorder.

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Myotonic dystrophy (autosomal dominant)I1I2II1II2II3Unaffected maleUnaffected femaleAffectedCarrierConsistent with 2 modes — autosomal dominant, autosomal recessive.Consistent with 2 modes: autosomal dominant, autosomal recessive. The other 4 modes are refuted — X-l…X-linked dominant is ruled out: I1 and his son II3 are both affected. A father gives his son a Y chro…X-linked recessive is ruled out: I1 and his son II3 are both affected, and a father gives his son a Y…Mitochondrial is ruled out: II1 is affected and their mother I2 is not. Mitochondria come from the eg…Y-linked is ruled out: II2 is an unaffected son of the affected I1. A Y-linked trait passes to every …

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title "Myotonic dystrophy (autosomal dominant)"
individual I1 sex male affected yes gen 1
individual I2 sex female affected no gen 1
mating I1 I2
individual II1 sex female affected yes gen 2 parents I1 I2
individual II2 sex male affected no gen 2 parents I1 I2
individual II3 sex male affected yes gen 2 parents I1 I2