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Genetics pedigree templates

Biology — Pedigree: sickle-cell anaemia (AR)

Autosomal recessive — carrier (sickle-trait) parents.

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Sickle-cell anaemia (autosomal recessive)I1I2II1II2II3Unaffected maleUnaffected femaleAffectedCarrierConsistent with one mode only — autosomal recessive.Consistent with exactly one mode: autosomal recessive. The other 5 modes are refuted — autosomal domi…Autosomal dominant is ruled out: II1 is affected and neither parent is. Under a dominant mode one cop…X-linked dominant is ruled out: II1 is affected and neither parent is, which a dominant mode cannot p…X-linked recessive is ruled out: II1 is affected and her father I1 is not. A daughter's two X chromos…Mitochondrial is ruled out: II1 is affected and their mother I2 is not. Mitochondria come from the eg…+ 1 further findings not listed

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title "Sickle-cell anaemia (autosomal recessive)"
individual I1 sex male affected no carrier yes gen 1
individual I2 sex female affected no carrier yes gen 1
mating I1 I2
individual II1 sex female affected yes gen 2 parents I1 I2
individual II2 sex male affected no carrier yes gen 2 parents I1 I2
individual II3 sex female affected no gen 2 parents I1 I2