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Drug-interaction network templates

Drug-interactions — anaesthesia adjuncts

Common interactions among anaesthetic adjuncts.

Drug-interaction networkLife SciencesDrug-interaction network syntax docs
Template previewDrug-interaction network
Anaesthesia adjunct interactions↑ respiratory depression↑ hypotension / apnoea↑ hypotension / apnoeaCYP3A4 inhibition↑ midazolam exposure↑ NMB durationFentanylopioidMidazolambenzodiazepinePropofolhypnoticRocuroniumNMBErythromycinmacrolideminormoderatemajorcontraindicated

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title "Anaesthesia adjunct interactions"
drug F "Fentanyl"       class opioid
drug M "Midazolam"      class benzodiazepine
drug P "Propofol"       class hypnotic
drug R "Rocuronium"     class NMB
drug E "Erythromycin"   class macrolide

interact F M "↑ respiratory depression" severity major
interact F P "↑ hypotension / apnoea"   severity major
interact M P "↑ hypotension / apnoea"   severity major
interact M E "↑ midazolam exposure"     severity major  mechanism "CYP3A4 inhibition"
interact R F "↑ NMB duration"           severity minor