ARRIVE — Animal Study

Animal-allocation diagram following ARRIVE 2.0 reporting guidelines.

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flowchart TD
P[Pre-study N = 80 mice] --> A[Randomly allocated]
A --> C[Control n = 40]
A --> T[Treatment n = 40]
C --> CO[Outcome measured\nn = 38]
C --> CL[Excluded n = 2 — anaesthesia]
T --> TO[Outcome measured\nn = 36]
T --> TL[Excluded n = 4 — humane endpoint]
CO --> AC[Analysed n = 38]
TO --> AT[Analysed n = 36]