Roadmap — Biotech R&D Pipeline by Asset and Phase
A five-year R&D portfolio roadmap for a fictional biotech with one lane per asset — an oral MASH candidate in Phase 2b, an antibody in Phase 1 and an oncology programme in IND-enabling studies — plus CMC and medical affairs: 13 items (2 done, 4 in progress, 6 planned, 1 at risk) and 6 milestones by half-year, status date 10 Feb 2027. All 14 dependencies finish before their dependents start, with each data readout gating the next phase, and the longest chain runs from the Phase 2b study through readout and the end-of-Phase 2 meeting to Phase 3. Illustrative roadmap.
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title "Corvane Therapeutics — R&D pipeline roadmap"
subtitle "Three clinical assets and the platform work behind them · each readout gates the next phase"
note "Illustrative example: Corvane Therapeutics and its assets are fictional; trial sizes, durations and dates are invented and are not regulatory advice."
axis halves H1 2026 .. H2 2030
today 2027-02-10
milestone seriesc "Series C financing closed" 2026-03-20 done
milestone review "Portfolio review with the board" 2027-12-10 planned after readout
lane "CVN-101 · MASH, oral" color: emerald
item p2b "Phase 2b dose-ranging, n = 240, 52 weeks" H1 2026 .. H1 2027 in progress 80% owner: "Clinical operations"
milestone readout "Phase 2b topline readout" 2027-07-30 planned after p2b
milestone eop2 "End-of-Phase 2 meeting" 2027-11-30 planned after readout
item p3 "Phase 3 registrational programme" H1 2028 .. H2 2030 planned after eop2
lane "CVN-204 · atopic dermatitis, antibody" color: violet
item sad "Phase 1 SAD/MAD in healthy volunteers" H2 2026 .. H1 2027 in progress 60%
item p2a "Phase 2a proof of concept, n = 120" H2 2027 .. H2 2028 planned after sad
milestone poc "Proof-of-concept readout" 2029-03-29 planned after p2a
item partner "Partnering process for Phase 3" 2029-04 .. 2029-12 planned after poc
lane "CVN-310 · solid tumours, preclinical" color: rose
item lead "Lead optimisation" H1 2026 done
item tox "IND-enabling GLP toxicology" H2 2026 .. H1 2027 at risk after lead owner: "Nonclinical"
milestone ind "IND submission" 2027-09-30 planned after tox, cmc310
item fih "First-in-human dose escalation" H1 2028 .. H2 2029 planned after ind
lane "CMC and manufacturing" color: amber
item api "Commercial-scale API process for CVN-101" H2 2026 .. H2 2027 in progress 30%
item ppq "Process performance qualification" H1 2028 planned after api
item cmc310 "GMP drug product for CVN-310" 2027-01 .. 2027-08 in progress 10%
lane "Medical affairs" color: sky
item registry "MASH natural-history registry" H1 2026 .. H2 2026 done
item heor "Health-economic model for MASH" H1 2029 .. H2 2029 planned after registry, eop2