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Causal DAG templates

Biology — Causal DAG: Healthy-Vaccinee Bias

Why observational vaccine studies can mislead.

Template previewCausal DAG
Healthy-vaccinee biasEVaccinationDO NOT ADJUSTODeathDO NOT ADJUSTHUnderlying healthFFrailtyExposureOutcomeConfounderMediatorUnobservedNo simple identification strategy works here: no adjustment set blocks every backdoor path, no front door is open, and nothing in this diagram…No simple identification strategy works for the effect of `Vaccination` on `Death`. Three doors were tried and all three are shut: no set of the observed variable…

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title "Healthy-vaccinee bias"
exposure E "Vaccination"
outcome O "Death"
confounder H "Underlying health"
unobserved F "Frailty"
E -> O
H -> E
H -> O
F -> E
F -> O