Biology — cAMP Second-Messenger Pathway
GPCR signalling through adenylyl cyclase and PKA.
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{
"elements":[
{"data":{"id":"hormone","label":"Hormone (e.g. adrenaline)"}},
{"data":{"id":"gpcr","label":"GPCR"}},
{"data":{"id":"gs","label":"Gs protein"}},
{"data":{"id":"ac","label":"Adenylyl cyclase"}},
{"data":{"id":"camp","label":"cAMP"}},
{"data":{"id":"pka","label":"Protein kinase A"}},
{"data":{"id":"response","label":"Phosphorylation -> response"}},
{"data":{"source":"hormone","target":"gpcr"}},
{"data":{"source":"gpcr","target":"gs"}},
{"data":{"source":"gs","target":"ac"}},
{"data":{"source":"ac","target":"camp"}},
{"data":{"source":"camp","target":"pka"}},
{"data":{"source":"pka","target":"response"}}
],
"layout":{"name":"breadthfirst","directed":true}
}