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Drug-interaction network templates

Biology — CYP Enzyme Inducers

Inducers speed metabolism and lower drug levels.

Template previewDrug-interaction network
CYP enzyme inducersfaster metabolismreduced effectCYP3A4 inductionloss of efficacyloss of efficacylower drug levelsEnzyme inducerinducerRifampicinantibioticCarbamazepineantiepilepticWarfarinanticoagulantOral contraceptivecontraceptiveminormoderatemajorcontraindicated

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title "CYP enzyme inducers"
drug I "Enzyme inducer"     class inducer
drug R "Rifampicin"         class antibiotic
drug C "Carbamazepine"      class antiepileptic
drug W "Warfarin"           class anticoagulant
drug O "Oral contraceptive" class contraceptive

interact R W "reduced effect" severity major mechanism "faster metabolism"
interact C O "loss of efficacy" severity major mechanism "CYP3A4 induction"
interact R O "loss of efficacy" severity major
interact I W "lower drug levels" severity moderate