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Drug-interaction network templates

Biology — Fluoroquinolone Interactions

Chelation, CYP1A2 and tendon hazards.

Drug-interaction networkLife SciencesDrug-interaction network syntax docs
Template previewDrug-interaction network
Fluoroquinolone interactionsCYP1A2 inhibitiontheophylline toxicitycation chelationreduced absorptionrise in INRadditivetendon ruptureCiprofloxacinantibioticTheophyllinebronchodilatorAntacidantacidWarfarinanticoagulantSteroidsteroidminormoderatemajorcontraindicated

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title "Fluoroquinolone interactions"
drug C "Ciprofloxacin" class antibiotic
drug T "Theophylline"  class bronchodilator
drug A "Antacid"       class antacid
drug W "Warfarin"      class anticoagulant
drug S "Steroid"       class steroid

interact C T "theophylline toxicity" severity major mechanism "CYP1A2 inhibition"
interact C A "reduced absorption" severity moderate mechanism "cation chelation"
interact C W "rise in INR" severity moderate
interact C S "tendon rupture" severity moderate mechanism "additive"