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Drug-interaction network templates

Biology — Calcium-Channel Blocker Interactions

Verapamil-centred cardiac and CYP3A4 interactions.

Drug-interaction networkLife SciencesDrug-interaction network syntax docs
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Calcium-channel blocker interactionsbradycardia / asystoleraised digoxin levelsdigoxin toxicityCYP3A4 inhibitionmyopathygut CYP3A4raised levelsVerapamilcalcium-blockerBeta blockerantihypertensiveDigoxincardiac-glycosideSimvastatinstatinGrapefruitfoodminormoderatemajorcontraindicated

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title "Calcium-channel blocker interactions"
drug V "Verapamil"    class calcium-blocker
drug B "Beta blocker" class antihypertensive
drug D "Digoxin"      class cardiac-glycoside
drug S "Simvastatin"  class statin
drug G "Grapefruit"   class food

interact V B "bradycardia / asystole" severity major
interact V D "digoxin toxicity" severity major mechanism "raised digoxin levels"
interact V S "myopathy" severity major mechanism "CYP3A4 inhibition"
interact V G "raised levels" severity moderate mechanism "gut CYP3A4"