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Drug-interaction network templates

Biology — Heart-Failure Drug Interactions

Interactions in chronic heart-failure therapy.

Drug-interaction networkLife SciencesDrug-interaction network syntax docs
Template previewDrug-interaction network
Heart failure interactionshyperkalaemiahypokalaemiadigoxin toxicityfluid retentionworsens failureadditive (intended)ACE inhibitorantihypertensiveSpironolactonediureticDigoxincardiac-glycosideLoop diureticdiureticNSAIDanalgesicminormoderatemajorcontraindicated

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title "Heart failure interactions"
drug A "ACE inhibitor"  class antihypertensive
drug S "Spironolactone" class diuretic
drug D "Digoxin"        class cardiac-glycoside
drug L "Loop diuretic"  class diuretic
drug N "NSAID"          class analgesic

interact A S "hyperkalaemia" severity major
interact L D "digoxin toxicity" severity major mechanism "hypokalaemia"
interact N A "worsens failure" severity major mechanism "fluid retention"
interact A L "additive (intended)" severity minor