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Drug-interaction network templates

Biology — Drugs in Liver Impairment

Drugs handled poorly by a damaged liver.

Template previewDrug-interaction network
Drugs in hepatic impairmenthepatotoxicity riskraised levels / myopathyfewer clotting factorsexaggerated INRprolonged sedationReduced liver functionorganParacetamolanalgesicStatinstatinWarfarinanticoagulantBenzodiazepinesedativeminormoderatemajorcontraindicated

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title "Drugs in hepatic impairment"
drug L "Reduced liver function" class organ
drug P "Paracetamol"    class analgesic
drug S "Statin"         class statin
drug W "Warfarin"       class anticoagulant
drug B "Benzodiazepine" class sedative

interact L P "hepatotoxicity risk" severity major
interact L S "raised levels / myopathy" severity moderate
interact L W "exaggerated INR" severity major mechanism "fewer clotting factors"
interact L B "prolonged sedation" severity moderate