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Drug-interaction network templates

Biology — St John's Wort Interactions

A potent herbal enzyme inducer.

Drug-interaction networkLife SciencesDrug-interaction network syntax docs
Template previewDrug-interaction network
St John's Wort interactionsCYP3A4 inductionloss of efficacyCYP3A4 inductiontransplant rejectionfall in INRserotonin syndromeSt Johns WortherbalOral contraceptivecontraceptiveCiclosporinimmunosuppressantWarfarinanticoagulantSSRIantidepressantminormoderatemajorcontraindicated

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title "St John's Wort interactions"
drug J "St Johns Wort"      class herbal
drug O "Oral contraceptive" class contraceptive
drug C "Ciclosporin"        class immunosuppressant
drug W "Warfarin"           class anticoagulant
drug S "SSRI"               class antidepressant

interact J O "loss of efficacy" severity major mechanism "CYP3A4 induction"
interact J C "transplant rejection" severity major mechanism "CYP3A4 induction"
interact J W "fall in INR" severity major
interact J S "serotonin syndrome" severity major