STROBE — Observational Study

flowchart TD
A[Source population\nN = 24,512] --> B[Eligible after inclusion criteria\nN = 8,304]
B --> C{Consent obtained}
C -- no --> Excl1[Refused\nn = 612]
C -- yes --> D[Enrolled\nN = 7,692]
D --> E{Baseline data complete}
E -- no --> Excl2[Excluded — missing data\nn = 184]
E -- yes --> F[Analysed cohort\nN = 7,508]
F --> G[Followed up at 12 months\nN = 6,941]
G --> H[Outcome events\nn = 412]