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Drug-interaction network templates

Biology — Antiemetic Interactions

QT and extrapyramidal risks with antiemetics.

Drug-interaction networkLife SciencesDrug-interaction network syntax docs
Template previewDrug-interaction network
Antiemetic interactionsQT prolongationserotonin syndromedopamine blockadeextrapyramidal effectscombinationOndansetronantiemeticMetoclopramideantiemeticQT drugantiarrhythmicAntipsychoticantipsychoticSSRIantidepressantminormoderatemajorcontraindicated

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title "Antiemetic interactions"
drug O "Ondansetron"    class antiemetic
drug M "Metoclopramide" class antiemetic
drug Q "QT drug"        class antiarrhythmic
drug A "Antipsychotic"  class antipsychotic
drug S "SSRI"           class antidepressant

interact O Q "QT prolongation" severity major
interact O S "serotonin syndrome" severity moderate
interact M A "extrapyramidal effects" severity major mechanism "dopamine blockade"
interact M O "combination" severity minor