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Drug-interaction network templates

Biology — Antiplatelet & Bleeding Risk

Stacking antithrombotic agents raises bleeding risk.

Drug-interaction networkLife SciencesDrug-interaction network syntax docs
Template previewDrug-interaction network
Antiplatelet interactionsdual antiplateletrise in bleedingrise in bleedinggastric injuryGI bleedingCYP2C19 inhibitionloss of efficacyAspirinantiplateletClopidogrelantiplateletWarfarinanticoagulantNSAIDanalgesicPPIantacidminormoderatemajorcontraindicated

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title "Antiplatelet interactions"
drug A "Aspirin"      class antiplatelet
drug C "Clopidogrel"  class antiplatelet
drug W "Warfarin"     class anticoagulant
drug N "NSAID"        class analgesic
drug P "PPI"          class antacid

interact A C "rise in bleeding" severity major mechanism "dual antiplatelet"
interact A W "rise in bleeding" severity major
interact A N "GI bleeding" severity major mechanism "gastric injury"
interact C P "loss of efficacy" severity moderate mechanism "CYP2C19 inhibition"