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Drug-interaction network templates

Biology — Antihypertensive Interactions

Interactions affecting blood-pressure control.

Template previewDrug-interaction network
Antihypertensive interactionsNa/water retentionreduced BP controlhyperkalaemiareduced effectintended combinationadditive BP dropadditive BP dropACE inhibitorantihypertensiveThiazidediureticNSAIDanalgesicPotassiumsupplementBeta blockerantihypertensiveminormoderatemajorcontraindicated

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title "Antihypertensive interactions"
drug A "ACE inhibitor" class antihypertensive
drug D "Thiazide"      class diuretic
drug N "NSAID"         class analgesic
drug K "Potassium"     class supplement
drug B "Beta blocker"  class antihypertensive

interact A N "reduced BP control" severity moderate mechanism "Na/water retention"
interact A K "hyperkalaemia" severity major
interact D N "reduced effect" severity moderate
interact A D "additive BP drop" severity minor mechanism "intended combination"
interact B D "additive BP drop" severity minor