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Drug-interaction network templates

Biology — Contraceptive Failure Risks

Enzyme inducers that reduce oral contraceptive efficacy.

Drug-interaction networkLife SciencesDrug-interaction network syntax docs
Template previewDrug-interaction network
Oral contraceptive interactionsCYP3A4 inductionloss of efficacyenzyme inductionloss of efficacyCYP3A4 inductionloss of efficacygut flora (debated)loss of efficacyCombined pillcontraceptiveRifampicinantibioticCarbamazepineantiepilepticSt Johns WortherbalAntibioticantibioticminormoderatemajorcontraindicated

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title "Oral contraceptive interactions"
drug O "Combined pill" class contraceptive
drug R "Rifampicin"   class antibiotic
drug C "Carbamazepine" class antiepileptic
drug J "St Johns Wort" class herbal
drug A "Antibiotic"   class antibiotic

interact O R "loss of efficacy" severity major mechanism "CYP3A4 induction"
interact O C "loss of efficacy" severity major mechanism "enzyme induction"
interact O J "loss of efficacy" severity major mechanism "CYP3A4 induction"
interact O A "loss of efficacy" severity minor mechanism "gut flora (debated)"