Skip to content
flowss
Start freeChecking your session
Drug-interaction network templates

Biology — Immunosuppressant Interactions

Transplant-drug interactions through CYP3A4 and toxicity.

Drug-interaction networkLife SciencesDrug-interaction network syntax docs
Template previewDrug-interaction network
Immunosuppressant interactionsCYP3A4 inhibitionrise in levelsCYP3A4 inhibitionrise in levelsCYP3A4 inductionloss of efficacyreduced statin clearancerise in myopathyCiclosporincalcineurin-inhibitorTacrolimuscalcineurin-inhibitorKetoconazoleantifungalRifampicinantibioticStatinlipid-loweringminormoderatemajorcontraindicated

Make it your own.

title "Immunosuppressant interactions"
drug C "Ciclosporin"  class calcineurin-inhibitor
drug T "Tacrolimus"   class calcineurin-inhibitor
drug K "Ketoconazole" class antifungal
drug R "Rifampicin"   class antibiotic
drug S "Statin"       class lipid-lowering

interact C K "rise in levels" severity major mechanism "CYP3A4 inhibition"
interact T K "rise in levels" severity major mechanism "CYP3A4 inhibition"
interact C R "loss of efficacy" severity major mechanism "CYP3A4 induction"
interact C S "rise in myopathy" severity major mechanism "reduced statin clearance"